Vitamin D supplementation in subjects with hypovitaminosis D: a randomized double-blind, placebo-controlled trial

Introduction: Despite having abundant sunshine all year long, hypovitaminosis D in Indonesia is still surprisingly prevalent. However, has been severely underdiagnosed and there were even fewer studies on its treatment. Thus, we aim to assess the effectiveness of daily vitamin supplementation for subjects with D.Method: A randomized double-blind, placebo-controlled trial conducted was a total 76 healthy, non-obese, working-age participants D. The intervention 1,000 IU D3 12 weeks, while placebo group received pill. serum 25(OH)D level measured pre-intervention, after 4 weeks intervention. data analyzed using an unpaired t-test SPSS version 24.0. Out 81 participants, (93.8%) have D.Result: treatment significantly higher than supplementation. delta also group. Furthermore, found be reduced at 12th week compared baseline. Participants who 1000 consecutive levels Same result observed when changes analyzed.Conclusion: Hypovitaminosis very prevalent among Indonesia.